Pennsylvania Breweries History: Pittsburgh Brewing Company The Pittsburgh Brewing Company was founded in Pittsburgh, Pennsylvania in 1861. In 1899 sixteen Pennsylvania breweries were merged into the Pittsburgh Brewing Company and the new brewery immediately became the nation's third largest brewer. In the 1940's and early 1950's, Pittsburgh Brewing Company suffered from a violent conflict between its brewer's union and the Teamsters. The Pittsburgh Brewing Company is currently the seventh largest brewery in the United States(as of 2003) and the only regional brewery that operates independently. Next to Heinz, the Pittsburgh Brewing Company utilizes more water than any other entity in the city of Pittsburgh PA. The Pittsburgh Brewing building represents a historic landmark in the city of Pittsburgh. The Pittsburgh Brewing brand of Iron City is an icon in the city of Pittsburgh. Some of the Pittsburgh Brewing brands are: Iron City, IC Light, IC Twist, plus JJ Wainwright's: Evil Eye Ale, Evil Eye Amber, Evil Honey Brown, Evil Eye Black & Tan.